CoQ10 Benefits for Fertility: Do Supplements Help?

Fertility challenges can be physically and emotionally overwhelming. Whether you’re exploring IVF, IUI, or trying to conceive naturally, it’s normal to wonder if supplements like CoQ10 for fertility can help. Research suggests this powerful antioxidant may play a meaningful role in improving egg and sperm health—two vital components in conception.

CoQ10, or coenzyme Q10, naturally occurs in every cell in the body and plays a critical role in energy production. Over the last decade, scientists have begun investigating its potential in reproductive medicine, particularly because fertility is closely tied to mitochondrial health. So, can CoQ10 supplements improve your chances of success with fertility treatments? Let’s break it down.

What Is CoQ10 and Why Is It Important for Fertility?

CoQ10 is a mitochondrial antioxidant that helps cells produce energy. Organs and cells that require a lot of energy—like eggs and sperm—depend heavily on CoQ10 for optimal function. As we age, the natural levels of CoQ10 in our body decline, which may lead to reduced cellular efficiency and increased oxidative stress, particularly in reproductive tissues.

This decline in CoQ10 levels is thought to contribute to poor egg quality, diminished ovarian reserve, and lower sperm health—key concerns for individuals and couples seeking fertility treatment.

CoQ10 Fertility Benefits for Women

Boosting Egg Quality

Egg cells contain more mitochondria than almost any other cell in the human body. These mitochondria need CoQ10 to produce the energy required for healthy division and embryo development. As women age, mitochondrial function diminishes, leading to an increase in chromosomal abnormalities and reduced embryo viability.

A study published in Fertility and Sterility found that supplementing with 600 mg of CoQ10 per day significantly improved egg quality in older women. The increased cellular energy production enhanced the fertilization process and embryo development.

Impact on IVF Success Rates

Research suggests that pretreatment with CoQ10 may improve the ovarian response to fertility medications. Women with diminished ovarian reserve who supplemented with CoQ10 prior to IVF showed better quality embryos and a higher fertilization rate.

Although more large-scale human studies are needed, the early evidence shows promise that CoQ10 benefits for fertility may translate into improved IVF outcomes, particularly in patients over age 35.

CoQ10 Fertility Benefits for Men

Sperm Health Improvements

Fertility isn’t only about egg quality. Male fertility is often affected by low sperm motility, count, and poor morphology—all of which are linked to oxidative stress.

CoQ10’s antioxidant power appears to combat these challenges. A study in the Journal of Andrology demonstrated that daily supplementation of 200–300 mg of CoQ10 significantly improved sperm motility and overall sperm health.

Another study published in The Journal of Urology found that CoQ10 therapy led to a marked improvement in both sperm density and motility, making it a potential ally for couples experiencing male factor infertility.

Should You Add CoQ10 to Your Fertility Plan?

Most fertility specialists now recommend CoQ10 for fertility support, particularly for individuals over 35 or those with a low ovarian reserve. CoQ10 is well-tolerated, with minimal side effects, and is often taken alongside a prenatal vitamin or fertility supplement regimen.

Common dosage guidelines include:

• Women: 600 mg daily (split into two or three doses)

• Men: 200–300 mg daily

While CoQ10 is available in two forms—Ubiquinone and Ubiquinol—the latter is more bioavailable and may be absorbed more efficiently by the body.

Before starting any supplement, consult with a fertility specialist to tailor your treatment plan and determine the right dosage and form for your unique needs.

A Promising Addition to Fertility Support

As research continues to explore CoQ10’s potential, the evidence so far supports its use as a safe and promising supplement for improving both egg and sperm health. For couples navigating fertility treatments or preparing for IVF, adding CoQ10 to your regimen may help enhance outcomes, especially when age or oxidative stress are concerns.

At Atlantic Reproductive Medicine, we stay at the forefront of integrative fertility solutions—helping you explore all options, including evidence-based supplementation. If you’re considering CoQ10 for fertility, reach out to our team to learn more and create a plan that’s right for you.

CoQ10 Fertility FAQs

Q: Is CoQ10 safe to take during IVF?
A: Yes, CoQ10 is generally safe and often recommended by fertility specialists to support egg quality during IVF cycles.

Q: How long should I take CoQ10 before starting fertility treatment?
A: It’s ideal to begin supplementation at least 2–3 months prior to starting IVF or other fertility treatments to allow time for cellular improvements.

Q: Can CoQ10 help with male infertility too?
A: Yes! CoQ10 has been shown to improve sperm count, motility, and morphology—key factors in male fertility.

Q: Are there any side effects of CoQ10 supplements?
A: CoQ10 is well-tolerated. Rare side effects may include mild digestive upset, especially if taken on an empty stomach.